PRP Therapy in IVF: Ovarian Rejuvenation Explained

PRP (Platelet-Rich Plasma) therapy has emerged as an innovative approach in IVF treatments, particularly for ovarian rejuvenation. PRP is derived from a patient’s own blood, concentrated to contain a high number of platelets rich in growth factors and bioactive proteins that promote tissue repair and regeneration. When injected into the ovaries, PRP aims to stimulate dormant follicles, improve ovarian function, and enhance egg quality. This technique offers new hope for women with diminished ovarian reserve or those experiencing age-related decline in fertility. By revitalizing the ovarian environment, PRP can increase the number of viable eggs available for retrieval, thereby potentially improving the chances of successful fertilization and pregnancy in IVF cycles. Although still under ongoing research, PRP therapy represents a promising and minimally invasive option to support reproductive health and boost IVF outcomes.

What is PRP Therapy and How is it Used in Assisted Reproduction?

PRP (Platelet-Rich Plasma) therapy is a regenerative treatment that utilizes a concentrated sample of a patient’s own blood, enriched with platelets containing growth factors and bioactive molecules essential for tissue healing and regeneration. In assisted reproduction, PRP is applied primarily to rejuvenate the ovaries by injecting it directly into ovarian tissue. This process aims to activate dormant follicles, improve blood flow, and enhance the ovarian microenvironment, which can lead to better egg quality and increased ovarian reserve. PRP therapy is especially considered for women with diminished ovarian reserve, poor response to ovarian stimulation, or those of advanced reproductive age. By supporting ovarian function naturally, PRP offers a promising adjunct to conventional IVF protocols, potentially increasing the chances of successful fertilization and pregnancy.

Who Can Benefit Most?

PRP therapy is especially beneficial for women with diminished ovarian reserve. It is often recommended for patients of advanced maternal age, those who have shown a poor response in previous IVF cycles, or women at risk of early ovarian failure. Additionally, it may help women with ovarian tissue damage or inadequate blood flow to the ovaries. However, PRP is not suitable for everyone; thorough medical evaluation and personalized treatment planning are essential before proceeding. When applied to the right candidates, PRP therapy can enhance fertility potential and improve IVF success rates.

Success Rates and Procedure Expectations

Success rates of PRP therapy in assisted reproduction are still being studied, but early clinical data show encouraging results, especially for women with low ovarian reserve or repeated IVF failures. Many patients report improved ovarian function, increased number of retrievable eggs, and better embryo quality following treatment. However, outcomes can vary depending on individual factors such as age, overall health, and underlying fertility issues. The procedure itself is minimally invasive, typically involving a simple blood draw followed by PRP preparation and ultrasound-guided injection into the ovaries. Recovery time is usually short, and patients can resume normal activities quickly. While PRP therapy offers promising potential, it is important to have realistic expectations and discuss personalized prognosis with a fertility specialist before starting treatment.